« Côte d'Ivoire: Govt Minister, OIE Report First Case of Bird FluAllAfrica News: Health and Medicine | Main | US: People expect H5N1 but don't lose sleep »

May 01, 2006

Molecular virology: Was the 1918 pandemic caused by a bird flu?Connotea: Bookmarks matching tag AvianFlu

 
Molecular virology: Was the 1918 pandemic caused by a bird flu? (info)
Mark Gibbs and Adrian Gibbs
Nature 440 (7088), E8 (27 Apr 2006)
Taubenberger et al.1 have sequenced the polymerase genes of the pandemic 'Spanish' influenza A virus of 1918, thereby completing the decoding of the genome of this virus2, 3, 4, 5, 6. The authors conclude from these sequences that the virus jumped from birds to humans shortly before the start of the pandemic and that it was not derived from earlier viruses by gene shuffling, a process called reassortment. However, we believe that their evidence does not convincingly support these conclusions and that some of their results even indicate that, on the contrary, the virus evolved in mammals before the pandemic began and that it was a reassortant. In light of this alternative interpretation, we suggest that the current intense surveillance of influenza viruses should be broadened to include mammalian sources.

Posted by dymaxion at May 1, 2006 09:02 PM

Trackback Pings

TrackBack URL for this entry:
http://www.dymaxionweb.com/cgi-bin/mtype/mt-tb.cgi/1715

Comments

Post a comment




Remember Me?