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July 27, 2006

Vaccine for H5N1 pandemic flu shows promise - New Zealand Doctor Online



Washington Post
Vaccine for H5N1 pandemic flu shows promise
New Zealand Doctor Online, New Zealand - 21 hours ago
GlaxoSmithKline plc today announced headline data showing its H5N1 pandemic flu vaccine achieved a high immune response at a low dose of antigen. ...
New H5N1 vaccine touted International Herald Tribune
New Bird Flu Vaccine Appears More Effective in Drug Trials NewsHour
Glaxo touts bird flu vaccine San Francisco Chronicle
Life Style Extra - Boston Globe - all 381 related

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Five new patients suspected of having caught deadly H5N1 - Bangkok Post



Thai News Agency MCOT
Five new patients suspected of having caught deadly H5N1
Bangkok Post, Thailand - 6 hours ago
Five new patients in Phitsanulok and Phichit, the provinces declared bird flu red zones, are suspected to have caught the H5N1 virus, doctors said yesterday. ...
Dengue impact on bird flu not yet known: Thai official People's Daily Online
Thailand intensifies inspection for bird flu outbreaks People's Daily Online
Thailand tries to improve bird flu monitoring Reuters AlertNet
Los Angeles Times - IHT ThaiDay - all 126 related

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More cats found with bird flu

 
More cats found with bird flu
www.nature.com
Posted by Declan and 1 other to cats AvianFlu H5N1 on Tue Jul 25 2006 at 21:26 UTC | info

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ABC News: Bird Flu Expert Says H5N1 Worst He's Seen

ABC News: Bird Flu Expert Says H5N1 Worst He's Seen (info). http://abcnews.go.com/Health/print?id=1923348. "I've worked with flu all my life, and this is the worst influenza virus that I have ever seen," said Webster, who has studied ...

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Who's Next at WHO?

Christine Gorman at Time Magazine speculates on the next leader of the World Health Organization: Who's Next at WHO? Excerpt:

Dr. Anders Nordstrom, a Swede, is filling the position in the interim, but in a mark of how desperate the organization is to fill the leadership void, a special election will be held for a new director-general on November 9.

Every country in the World Health Assembly—which includes almost everyone in the world—can nominate a candidates, who will then be winnowed down by the WHO's executive board before the assembly votes.

Contenders have already begun emerging, and today China nominated a candidate who may very well have the inside track: Dr. Margaret Chan, the WHO's current Director for Communicable Disease Surveillance and Response, and the organization's point person on pandemic influenza.

Before she joined the WHO in 2003, Chan was the Director of Health in Hong Kong from 1994, where she oversaw the local response to the world's original outbreak of H5N1 avian flu in 1997, and endured the SARS crisis in 2003.

She's smart, popular and—as I know from having interviewed her a few times—considerably more personable than the average WHO administrator.

Posted by dymaxion at 10:10 PM | Comments (0) | TrackBack

Thailand: PM blames flu outbreak on villagers

Via the Bangkok Post: PM blames flu outbreak on villagers. Excerpt:

Caretaker Prime Minister Thaksin Shinawatra yesterday blamed the fresh outbreak of bird flu in Phichit on alleged attempts by villagers to cover up suspected cases, while the Agriculture and Cooperatives Ministry acknowledged the need to improve its surveillance system.

Mr Thaksin said some villagers tried to cover up suspected bird flu cases for fear their fowls would be culled en masse.

Many poultry raisers in Phichit, the epicentre of the latest spread of bird flu, did not register their fowls with the provincial authority, and when their birds died of unknown causes they disposed of the carcasses themselves, he said.

Those villagers, therefore, exposed themselves to the risk of infection by the deadly virus, Mr Thaksin added.

es on to name the victim—Yongyuth Daenmisi—and describes the circumstances of his death:
According to the Public Health Ministry press release, Yongyuth developed a high fever with headaches on July 15, a week after he buried 10 dead chickens with his bare hands. He was hospitalised with flu-like and haemorrhagic symptoms four days later, but tested negative for bird flu then.

Thiravat Hemachudha, a neurologist at Chulalongkorn Hospital, criticised the authorities' heavy reliance on local volunteers without sufficient efforts to raise people's awareness of the disease on a continuous basis.

The case in which doctors failed to detect the deadly virus in Yongyuth showed there was a lack of awareness in his community, Dr Thiravat said.

a href= "http://www.nationmultimedia.com/2006/07/27/headlines/headlines_30009688.php">The Nation covers the same story and adds some details—including mention of yet another suspected human case:
Three blood tests by Phitsanulok Medical Science Centre had previously been negative for bird flu. The teenager's blood count showed he had dengue fever before yesterday's final test also confirmed H5N1.

On Tuesday, the Department of Livestock Development (DLD) said the H5N1 virus had been detected in poultry in Phichit.

All three people in the dead teenager's family have been receiving anti-viral drug Tamiflu. Pinij said that although they were in a healthy condition, public-health authorities would keep an eye on them for 14 days.

Meanwhile, Tap Klo Hospital in Phichit's Tap Klo district yesterday admitted a 9-year-old boy with symptoms similar to bird flu. Doctors are now awaiting the results of tests. The 17-year-old who died was also a resident of Thab Khlo district.

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July 19, 2006

Indonesian dies of H5N1 strain - News24


Indonesian dies of H5N1 strain
News24, South Africa - Jul 16, 2006
If confirmed by a World Health Organisation-approved laboratory, the man's death would bring the number of Indonesians killed by the H5N1 bird flu strain to at ...

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Multiple H5N1 mutations found in familial cluster of human ...

Multiple mutations were found in the H5N1 bird flu virus that killed seven family members in Indonesia, according to a confidential research obtained by the science ... Tags: avian flu, H5N1, Indonesia, mutations, World Health Organization.

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US: Get powers ready for bird flu, governors told

Via Reuters: Get powers ready for bird flu, U.S. governors told.

Governors should make sure they have the legal powers they need to impose quarantines, close schools and keep utilities and transport running in case of a bird flu pandemic, according to new primer from the National Governors' Association published on Tuesday.

They should also be working now on clear, simple public messages about the risks of bird flu and what preparations are being made as well as stocking up on food and medical supplies, the document advises.

"Governors should consider creating a state legal team to review current laws and regulations and assess how they would be applied during a pandemic," reads the primer, posted on the Internet at NGA.org.

"For example, decisions on closure of schools, limits on use or practices on mass transit or public transport systems, restrictions on public gatherings, etc., must be determined by state and local officials and supported by local or state policies and law."

Washington Post's story on the primer.

And here is the primer itself: Download 0607PANDEMICPRIMER.pdf

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Bird Flu Vaccine For Poultry Successfully Developed In India

 
Bird Flu Vaccine For Poultry Successfully Developed In India (info)
http://www.medicalnewstoday.com/healthnews.php?newsid=47451
The Indian Council of Agricultural Research (ICAR) said yesterday that it has successfully developed a vaccine that protects poultry from bird flu. The announcement was made during the 77th Annual General Meeting of the ICAR Society, by Shri Sharad Pawar, Union Minister of Agriculture.
Posted by ojcius to AvianFlu H5N1 india vaccine on Tue Jul 18 2006 at 03:21 UTC

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Thai chicken exports set to rise by about 30 pct this yr as bird flu fears ease - Forbes.com

 
Thai chicken exports set to rise by about 30 pct this yr as bird flu fears ease - Forbes.com (info)
http://www.forbes.com/business/feeds/afx/2006/07/17/afx2882522.html
Thailand said its chicken exports are expected to rise by almost 30 pct this year as concerns ease among key export markets over the deadly bird flu virus in the kingdom.
Posted by ojcius to poultry Thailand AvianFlu H5N1 on Mon Jul 17 2006 at 14:09 UTC

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Flu Stories: The Witholding of Flu Viral Sequences Filters Into ...

Dennis Kucinich (Democrat, Ohio) and Wayne Gilchrest (Republican, Maryland are circulating a letter in the House of Representatives that calls on Michael Levitt, the US health secretary, to require H5N1 sequences and other publicly ...

Posted by dymaxion at 10:13 PM | Comments (0) | TrackBack

Six states shy away from bird flu drugs - United Press International



World Fitness
Six states shy away from bird flu drugs
United Press International - 3 hours ago
... States have less than two weeks to announce their plans. The deadly H5N1 strain of the avian flu has killed scores worldwide. There ...
Bird flu pandemic could claim $800bln in first year alone – WHO TREND Information
all 8 related

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Thai senator suspects H5N1 coverup

Thanks to the readers who sent the link to this story in ThaiDay, a Thai news source: Bird flu has returned, suspects senator.

Outgoing Ubon Ratchathani senator Nirand Pitakwatchara said at the weekend that he believes bird flu has resurfaced in Thailand, but that state authorities have concealed the matter for political reasons.

Nirand, a former chairman of the senate committee on social development and human security, said it was most likely that the Agriculture Ministry, under Khunying Sudarat Keyuraphan, who was responsible for dealing with avian flu when she was Public Health Minister, has teamed up with the Public Health Ministry to cover up the reappearance of the disease to protect the Thai Rak Thai government.

“If bird flu has really come back, it means that all the government’s measures to prevent the disease have failed miserably,” said Nirand.

“It seems to me that the government’s previous actions were only meant to build up its image and gain political popularity,” he added.

The senator’s comments coincided with the disclosure by a livestock official who told a Phoojadkarn Daily reporter that bird flu has returned in Phichit and Phitsanulok provinces, killing poultry there in recent months.

Livestock officials have been told to keep their mouths shut as the news may affect the government’s stability and lead to a worsening of political and economic conditions, said the source, who asked not to be named.

nd is clearly no supporter of the present government, but it would be helpful to know more about his background: for example, has he taken similar shots before? And if so, has he been proven right or wrong?

Taken at face value, this is a disturbing report.

Posted by dymaxion at 10:03 PM | Comments (0) | TrackBack

July 10, 2006

India says nearly done on local bird flu vaccine

 
India says nearly done on local bird flu vaccine (info)
http://www.alertnet.org/thenews/newsdesk/SP175750.htm
India is close to developing its own vaccine against avian flu in poultry with final phase trials showing 90 percent success, the head of the country's top animal disease research laboratory said on Monday.
Posted by ojcius to AvianFlu H5N1 india vaccine on Mon Jul 10 2006 at 21:27 UTC

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H5N1 Bird Flu Infection In Humans May Rise Late 2006

The number human infections of the deadly H5N1 bird flu virus may increase dramatically later this year or early in 2007, the World Health Organization said in a recent online publication. The June 30 issue of the Weekly Epidemiological ...

Posted by dymaxion at 10:19 PM | Comments (0) | TrackBack

Indonesia bird flu poultry death rate rises

Via Reuters: Indonesia bird flu poultry death rate rises.

The poultry death rate from the H5N1 avian flu virus in Indonesia, the country with the most human bird flu deaths this year, is worsening, possibly due to poor vaccination coverage, a senior government official said on Thursday.

Mathur Riady, director-general of livestock production at the agriculture ministry, said one million fowl, half of them quail, died of bird flu in the first three months of 2006. In 2005, deaths for the year as a whole were 1.2 million.

"Based on the data, there is a tendency of a rise in bird flu-related deaths in poultry. It may be caused by low vaccination coverage, particularly in small farms and backyard chickens," Riady told reporters.

"But it may also be because the reporting system on poultry deaths is getting better."

Posted by dymaxion at 10:09 PM | Comments (0) | TrackBack

Avian Flu Claims Life of 5-Year-Old Indonesian BoyTechRepublic News

A World Health Organization laboratory has confirmed that a 5-year-old Indonesian boy who died last month was infected with bird flu, a Health Ministry spokesperson said Monday. The boy, who died on June 16 in the East Java provincial town of Tulungagung, was found positive for the H5N1 strain of bird flu in tests by the WHO reference laboratory in Hong Kong, spokesperson Sumardi said.

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July 05, 2006

WHO Confirms Another Bird Flu Victim in IndonesiaSci-Tech Today

The Indonesian government has confirmed another death in the country due to bird flu, an official said Monday.

The latest victim was a 5-year-old boy who died June 16 in Tulungagung, a town in East Java, said Nyoman Kandun of the Health Ministry.

A test by a WHO-affiliated laboratory in Hong Kong found that the boy was infected by the H5N1 virus, he said.

"We received the confirmation some two or three days ago," Kandun said.

The H5N1 virus is considered endemic in poultry in most provinces across the sprawling archipelago.

The latest victim brought Indonesia's human death toll from bird flu to 40, trailing only Vietnam, where 42 people have died of the disease.

Bird flu has killed at least 129 people worldwide since it started ravaging Asian poultry farms in late 2003.

Most human cases have been linked to contact with infected birds, but experts fear the virus could mutate into a form that makes it more easily transmissible among humans.

The World Bank has urged cash-strapped Indonesia to be more aggressive in culling fowl in infected areas -- something Jakarta has been unwilling to do so far due to a lack of funds.

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China: H5N1 "under control" in Xinjiang

The expert panel agreed that the quarantine and disinfection work were in accordance with national regulations, and confirmed that no more poultry had been identified with the H5N1 virus and no human cases had been found. ...

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Bird/Human H5N1 Cases Have Different Sequences

Recent independent analysis of the sequences of the H5N1 virus in Indonesia are indicating a mammalian infection route to humans as opposed to contact with birds.

Posted by dymaxion at 02:21 PM | Comments (0) | TrackBack

Bird Flu May Have Entered Nigeria 3 Times - Washington Post



Washington Post
Bird Flu May Have Entered Nigeria 3 Times
Washington Post, United States - 48 minutes ago
... three times. One expert said that suggests that the H5N1 virus spreads more efficiently than researchers had thought. Two unidentified ...

Posted by dymaxion at 02:19 PM | Comments (0) | TrackBack

Bird flu spreads to new state in Nigeria

Via Reuters: Bird flu spreads to new state in Nigeria.

The deadly H5N1 strain of bird flu has appeared in remote Taraba state in eastern Nigeria, but in most other parts of Africa's most populous country the spread of the virus is slow, officials said on Friday.

The first African country to be hit by bird flu, Nigeria has not reported any human cases of the disease although experts warn surveillance may not be completely effective and cases may have gone undetected. The detection of the virus in Taraba means bird flu is now present in 14 of Nigeria's 36 states and in the Federal Capital Territory. The state that had most recently joined the list was Lagos in April.

"We have identified it in three places in Taraba, one commercial farm and two places where there are backyard poultry," said Lami Lombin, director of the National Veterinary Research Institute which tests for bird flu.

es me almost as much as Indonesia. Western media seem to have zero interest in African news unless it involves thousands of deaths, and even then it depends on the cause of death. An overcrowded bus going into a ravine is news. People dying of cholera or AIDS in an overcrowded hospital are not news.

So H5N1 will keep eating away at African economies and communities without our noticing until something like an H2H outbreak finally gets our attention.

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Geographic / H 5 N1fatality Age Table IndonesiaFlu Wiki | Main / All Recent Changes

H5N1 Fatality Table for Indonesia by Age, Province, Gender and Date of Death Data was derived from the WHO and ProMed AgeProvinceGenderDate of Death 1.5Kar ...

Posted by dymaxion at 02:09 PM | Comments (0) | TrackBack

Mali: New new centre to tackle bird flu across AfricaH5N1

Via allAfrica.com, a story from IRIN: Mali: New Centre to Tackle Bird Flu Across Africa .

The World Organisation for Animal Health, or OIE, has set up its first regional control centre in Africa with the aim of coordinating measures against bird flu, which is threatening livelihoods and health across the continent.

Centre head Samba Sidibe told IRIN after the special opening in June that Africa is particularly vulnerable to the threat of the deadly H5N1 virus.

"Avian flu represents a serious threat to agriculture and in particular the fight against poverty," said Sidibe.

And often, said Sidibe, shortages of funds prevent the establishment of projects to tackle animal diseases such as bird flu.

The new centre to date is the OIE's only regional office in Africa. The OIE aims to collate and disseminate veterinary information and safeguard world trade by producing health guidelines for international trade in animals, among other things.

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Delaying the international spread of H5N1H5N1

Via Connotea, here is a new article in Public Library of Science Medicine: Delaying the International Spread of Pandemic Influenza. An excerpt from the abstract:

To evaluate the potential of local control measures and travel restrictions to impede global dissemination, we developed stochastic models of the international spread of influenza based on extensions of coupled epidemic transmission models. These models have been shown to be capable of accurately forecasting local and global spread of epidemic and pandemic influenza.

We show that under most scenarios restrictions on air travel are likely to be of surprisingly little value in delaying epidemics, unless almost all travel ceases very soon after epidemics are detected.

Interventions to reduce local transmission of influenza are likely to be more effective at reducing the rate of global spread and less vulnerable to implementation delays than air travel restrictions.

Nevertheless, under the most plausible scenarios, achievable delays are small compared with the time needed to accumulate substantial vaccine stocks.

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HHS has enough H5N1 vaccine for 4 million people - CIDRAP

... HHS has enough H5N1 vaccine for 4 million people CIDRAP, MN - 32 minutes ago ... In an update on pandemic influenza preparedness efforts, the federal government said last week it had stockpiled enough vaccine against H5N1 avian influenza ... ...
Pandemic Virus Facts and Information View Technorati URL search

Posted by dymaxion at 01:57 PM | Comments (0) | TrackBack

Bird-flu patient on the mend - Shanghai Daily

... Bird-flu patient on the mend Shanghai Daily, China - 26 minutes ago ... The Ministry of Health confirmed on June 15 that the 31-year-old surnamed Jiang had contracted the H5N1 strain of avian influenza, bringing China's total human ... HK to resume import of live poultry from Guangdong People's Daily Online all 3 related ...
Pandemic Virus Facts and Information View Technorati URL search

Posted by dymaxion at 01:57 PM | Comments (0) | TrackBack