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August 08, 2007

Human trials start for H5N1 DNA vaccine

Stories about experimental vaccines that "work in animals" are a dime a dozen these days. That's not bad. It means there is a lot of activity on the innovative technologies front. But there is a huge distance between "works in mice" and "works in humans." So news that one of these technologies is entering human trials, even small scale Phase I trials, is rarer. Recently we posted on the proposed start of Phase I clinical trials for a "universal flu vaccine" that works across subtypes (H5N1, H1N1, H3N2, etc.) as well as across drift variations within subtypes (the genetic differences seen from year to year in seasonal influenza, for example). Now a DNA vaccine, specifically for H5N1, is starting clinical trials at NIH:

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Posted by dymaxion at August 8, 2007 09:48 PM

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